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Anti-Human CBX2 Recombinant Antibody (SAA2130) (HC416013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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概述
货号HC416013
品牌abinScience
种属反应性Human
应用ELISA, IF, IP
宿主Mouse
克隆类型Monoclonal
同种型IgG2a
克隆号SAA2130
靶标CBX2, Chromobox protein homolog 2
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q14781
RRIDAnti-Human CBX2 Antibody (SAA2130) (abinScience Cat# HC416013, RRID:AB_3729483)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Chromobox protein homolog 2 (CBX2) is a ~56 kDa protein. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression.

1. Vandamme, J. et al. (2011) Molecular & cellular proteomics : MCP 10, M110.002642. PMID: 21282530
2. Biason-Lauber, A. et al. (2009) American journal of human genetics 84, 658-63. PMID: 19361780
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CBX2 Antibody (SAA2130)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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