Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188) (HC673013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HC673013

abinScience

种属反应性

Human, Mouse

ELISA, IF, IP

Mouse

Monoclonal

SAA0188

Fetal Alzheimer antigen, FALZ, Nucleosome-remodeling factor subunit BPTF, FAC1, BPTF, Fetal Alz-50 clone 1 protein, Bromodomain and PHD finger-containing transcription factor

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q12830

Anti-Human FALZ/BPTF IP Antibody (SAA0188) (abinScience Cat# HC673013, RRID:AB_3729722)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Nucleosome-remodeling factor subunit BPTF (FALZ) is a ~338 kDa protein. Regulatory subunit of the ATP-dependent NURF-1 and NURF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The NURF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NURF-5 ISWI chromatin remodeling complex. Within the NURF-1 ISWI chromatin-remodeling complex, binds to the promoters of En1 and En2 to positively regulate their expression and promote brain development. Histone-binding protein which binds to H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of active genes. Binds to histone H3 tails dimethylated on 'Lys-4' (H3K4Me2) to a lesser extent.

1. Barak, O. et al. (2003) The EMBO journal 22, 6089-100. PMID: 14609955

2. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535

3. Wysocka, J. et al. (2006) Nature 442, 86-90. PMID: 16728976

4. Li, H. et al. (2006) Nature 442, 91-5. PMID: 16728978

5. Li, H. et al. (2007) Molecular cell 28, 677-91. PMID: 18042461

6. Jordan-Sciutto, KL. et al. (1999) The Journal of biological chemistry 274, 35262-8. PMID: 10575013

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human FALZ/BPTF IP Antibody (SAA0188)

产品说明书

Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188) (HC673013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FALZ/BPTF IP Recombinant Antibody (SAA0188) (HC673013)

概述

图片

参考文献

产品说明书

相关产品推荐

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