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Anti-Human CIAO1 IP Recombinant Antibody (SAA0198) (HF508013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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  • 参考文献

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概述
货号HF508013
品牌abinScience
种属反应性Human
应用ELISA, IF, IP
宿主Mouse
克隆类型Monoclonal
同种型IgG2a
克隆号SAA0198
靶标WD repeat-containing protein 39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WDR39, CIA1, CIAO1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O76071
RRIDAnti-Human CIAO1 IP Antibody (SAA0198) (abinScience Cat# HF508013, RRID:AB_3729732)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a ~37 kDa protein. Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1.

1. Srinivasan, V. et al. (2007) Structure (London, England : 1993) 15, 1246-57. PMID: 17937914
2. Stehling, O. et al. (2013) Cell metabolism 18, 187-98. PMID: 23891004
3. Maio, N. et al. (2024) The Journal of clinical investigation 134. PMID: 38950322
4. Johnstone, RW. et al. (1998) The Journal of biological chemistry 273, 10880-7. PMID: 9556563
5. Ito, S. et al. (2010) Molecular cell 39, 632-40. PMID: 20797633
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CIAO1 IP Antibody (SAA0198)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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