

| 货号 | HP484013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA, IF, IP, IP-MS | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG | ||||
| 克隆号 | SAA0200 | ||||
| 靶标 | DOT1-like protein, Lysine N-methyltransferase 4, DOT1L, Histone-lysine N-methyltransferase, H3 lysine-79 specific, KMT4, H3-K79-HMTase, KIAA1814, Histone H3-K79 methyltransferase | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q8TEK3 | ||||
| RRID | Anti-Human DOT1L IP Antibody (SAA0200) (abinScience Cat# HP484013, RRID:AB_3729734) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Histone-lysine N-methyltransferase, H3 lysine-79 specific (DOT1L) is a ~164 kDa protein. Histone methyltransferase that methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. 1. Feng, Q. et al. (2002) Current biology : CB 12, 1052-8. PMID: 12123582 2. Frisbie, VS. et al. (2024) Nature communications 15, 2467. PMID: 38503750 3. Singh, PR. et al. (2023) Nature communications 14, 8497. PMID: 38129415 4. Min, J. et al. (2003) Cell 112, 711-23. PMID: 12628190 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507) |

SDS-PAGE for Anti-Human DOT1L IP Antibody (SAA0200)



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