Anti-Human HACE1 IP Recombinant Antibody (SAA0202) (HP555013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HP555013

abinScience

种属反应性

Human

ELISA, IF, IP

Mouse

Monoclonal

SAA0202

HECT-type E3 ubiquitin transferase HACE1, HACE1, E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, KIAA1320

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q8IYU2

Anti-Human HACE1 IP Antibody (SAA0202) (abinScience Cat# HP555013, RRID:AB_3729736)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

E3 ubiquitin-protein ligase HACE1 is a ~102 kDa protein. E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically binds GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

1. Anglesio, MS. et al. (2004) Human molecular genetics 13, 2061-74. PMID: 15254018

2. Tang, D. et al. (2011) Nature communications 2, 501. PMID: 21988917

3. Torrino, S. et al. (2011) Developmental cell 21, 959-65. PMID: 22036506

4. Singh, S. et al. (2023) Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10, e2207672. PMID: 37537642

5. Düring, J. et al. (2024) Nature structural & molecular biology 31, 364-377. PMID: 38332367

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human HACE1 IP Antibody (SAA0202)

产品说明书

Anti-Human HACE1 IP Recombinant Antibody (SAA0202).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HACE1 IP Recombinant Antibody (SAA0202) (HP555013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HACE1 IP Recombinant Antibody (SAA0202) (HP555013)

概述

图片

参考文献

产品说明书

相关产品推荐

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