Anti-Human L3MBTL3 IP Recombinant Antibody (SAA0209) (HP399013)

价格:

规格：

50ug
100ug
1mg

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HP399013

abinScience

种属反应性

Human

ELISA, IF, IP, IP-MS

Mouse

Monoclonal

SAA0209

Lethal(3)malignant brain tumor-like protein 3, H-l(3)mbt-like protein 3, KIAA1798, L3MBTL3, L3mbt-like 3, MBT-1, L(3)mbt-like protein 3, MBT1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q96JM7

Anti-Human L3MBTL3 IP Antibody (SAA0209) (abinScience Cat# HP399013, RRID:AB_3729743)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) is a ~88 kDa protein. Is a negative regulator of Notch target genes expression, required for RBPJ-mediated transcriptional repression. It recruits KDM1A to Notch-responsive elements and promotes KDM1A-mediated H3K4me demethylation. Involved in the regulation of ubiquitin-dependent degradation of a set of methylated non-histone proteins, including SOX2, DNMT1 and E2F1. It acts as an adapter recruiting the CRL4-DCAF5 E3 ubiquitin ligase complex to methylated target proteins. Required for normal maturation of myeloid progenitor cells.

1. Xu, T. et al. (2017) The EMBO journal 36, 3232-3249. PMID: 29030483

2. Leng, F. et al. (2018) Nature communications 9, 1641. PMID: 29691401

3. Zhang, C. et al. (2019) The Journal of biological chemistry 294, 476-489. PMID: 30442713

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human L3MBTL3 IP Antibody (SAA0209)

产品说明书

Anti-Human L3MBTL3 IP Recombinant Antibody (SAA0209).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human L3MBTL3 IP Recombinant Antibody (SAA0209) (HP399013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human L3MBTL3 IP Recombinant Antibody (SAA0209) (HP399013)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价