Anti-Human PARP14 IP Recombinant Antibody (SAA0213) (HS727013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HS727013

abinScience

种属反应性

Human

ELISA, IF, IP

Mouse

Monoclonal

SAA0213

BAL2, B aggressive lymphoma protein 2, PARP14, Poly [ADP-ribose] polymerase 14, Protein mono-ADP-ribosyltransferase PARP14, PARP-14, ADP-ribosyltransferase diphtheria toxin-like 8, KIAA1268, ARTD8

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q460N5

Anti-Human PARP14 IP Antibody (SAA0213) (abinScience Cat# HS727013, RRID:AB_3729747)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Protein mono-ADP-ribosyltransferase PARP14 is a ~202 kDa protein. ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate residues on target proteins. In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation. Has been shown to catalyze the mono-ADP-ribosylation of STAT1 at 'Glu-657' and 'Glu-705', thus decreasing STAT1 phosphorylation which negatively regulates pro-inflammatory cytokine production in macrophages in response to IFNG stimulation. However, the role of ADP-ribosylation in the prevention of STAT1 phosphorylation has been called into question and it has been suggested that the inhibition of phosphorylation may be the result of sumoylation of STAT1 'Lys-703'. Mono-ADP-ribosylates STAT6; enhancing STAT6-dependent transcription.

1. Aguiar, RC. et al. (2005) The Journal of biological chemistry 280, 33756-65. PMID: 16061477

2. Kleine, H. et al. (2008) Molecular cell 32, 57-69. PMID: 18851833

3. Vyas, S. et al. (2014) Nature communications 5, 4426. PMID: 25043379

4. Iwata, H. et al. (2016) Nature communications 7, 12849. PMID: 27796300

5. Begitt, A. et al. (2018) Nature communications 9, 2144. PMID: 29858569

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human PARP14 IP Antibody (SAA0213)

产品说明书

Anti-Human PARP14 IP Recombinant Antibody (SAA0213).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PARP14 IP Recombinant Antibody (SAA0213) (HS727013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PARP14 IP Recombinant Antibody (SAA0213) (HS727013)

概述

图片

参考文献

产品说明书

相关产品推荐

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