首页 > 产品中心 > 抗体 > 重组单抗

Anti-Human PHF8 IP Recombinant Antibody (SAA0216) (HP682013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HP682013
品牌abinScience
种属反应性Human
应用ELISA, IF, IP
宿主Mouse
克隆类型Monoclonal
同种型IgG2a
克隆号SAA0216
靶标[histone H3]-dimethyl-L-lysine(9) demethylase PHF8, KIAA1111, [histone H3]-dimethyl-L-lysine(36) demethylase PHF8, PHF8, ZNF422, Histone lysine demethylase PHF8, PHD finger protein 8
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9UPP1
RRIDAnti-Human PHF8 IP Antibody (SAA0216) (abinScience Cat# HP682013, RRID:AB_3729750)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Histone lysine demethylase PHF8 is a ~117 kDa protein. Histone lysine demethylase with selectivity for mono- and dimethylated residues. It plays an essential role in cell cycle progression and rDNA transcription. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Displays a very low intrinsic activity toward dimethylated H3 'Lys-27' (H3K27Me2).

1. Loenarz, C. et al. (2010) Human molecular genetics 19, 217-22. PMID: 19843542
2. Zhu, Z. et al. (2010) Cell research 20, 794-801. PMID: 20531378
3. Qiu, J. et al. (2010) Cell research 20, 908-18. PMID: 20548336
4. Liu, W. et al. (2010) Nature 466, 508-12. PMID: 20622854
5. Yu, L. et al. (2010) Cell research 20, 166-73. PMID: 20101266
6. Feng, W. et al. (2010) Nature structural & molecular biology 17, 445-50. PMID: 20208542
7. Kleine-Kohlbrecher, D. et al. (2010) Molecular cell 38, 165-78. PMID: 20346720
8. Qi, HH. et al. (2010) Nature 466, 503-7. PMID: 20622853
9. Horton, JR. et al. (2010) Nature structural & molecular biology 17, 38-43. PMID: 20023638
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human PHF8 IP Antibody (SAA0216)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐