Anti-Human ASF1B IP Recombinant Antibody (SAA0242) (HP847013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HP847013

abinScience

种属反应性

Human

ELISA, IF, IP

Mouse

Monoclonal

IgG2a

SAA0242

ASF1B, hAsf1, hCIA-II, CIA-II, hAsf1b, Histone chaperone ASF1B, Anti-silencing function protein 1 homolog B, CCG1-interacting factor A-II

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9NVP2

Anti-Human ASF1B IP Antibody (SAA0242) (abinScience Cat# HP847013, RRID:AB_3729776)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Histone chaperone ASF1B is a ~22 kDa protein. Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for gonad development.

1. Mello, JA. et al. (2002) EMBO reports 3, 329-34. PMID: 11897662

2. Tagami, H. et al. (2004) Cell 116, 51-61. PMID: 14718166

3. Groth, A. et al. (2005) Molecular cell 17, 301-11. PMID: 15664198

4. Tamburini, BA. et al. (2005) Eukaryotic cell 4, 1583-90. PMID: 16151251

5. Alvarez, F. et al. (2011) The Journal of biological chemistry 286, 17714-21. PMID: 21454524

6. Campos, EI. et al. (2015) Molecular cell 60, 697-709. PMID: 26527279

7. Campos, EI. et al. (2010) Nature structural & molecular biology 17, 1343-51. PMID: 20953179

8. Umehara, T. et al. (2003) The Journal of biological chemistry 278, 35660-7. PMID: 12842904

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human ASF1B IP Antibody (SAA0242)

产品说明书

Anti-Human ASF1B IP Recombinant Antibody (SAA0242).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ASF1B IP Recombinant Antibody (SAA0242) (HP847013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ASF1B IP Recombinant Antibody (SAA0242) (HP847013)

概述

图片

参考文献

产品说明书

相关产品推荐

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