Anti-Human TIF1/TRIM24 IP Recombinant Antibody (SAA0265) (HT332013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HT332013

abinScience

种属反应性

Human

ELISA, IF, IP

Mouse

Monoclonal

IgG2a

SAA0265

RING-type E3 ubiquitin transferase TIF1-alpha, TIF1-alpha, RING finger protein 82, Transcription intermediary factor 1-alpha, RNF82, Tripartite motif-containing protein 24, E3 ubiquitin-protein ligase TRIM24, TIF1, TIF1A, TRIM24

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O15164

Anti-Human TIF1/TRIM24 IP Antibody (SAA0265) (abinScience Cat# HT332013, RRID:AB_3729799)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Transcription intermediary factor 1-alpha (TIF1/TRIM24) is a ~116 kDa protein. Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. During the DNA damage response, participates in an autoregulatory feedback loop with TP53. Early in response to DNA damage, ATM kinase phosphorylates TRIM24 leading to its ubiquitination and degradation.

1. Jain, AK. et al. (2014) Molecular and cellular biology 34, 2695-709. PMID: 24820418

2. Zhu, Q. et al. (2020) The Journal of experimental medicine 217. PMID: 32324863

3. Hang, Y. et al. (2021) Cell biology international 45, 1561-1570. PMID: 33724611

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human TIF1/TRIM24 IP Antibody (SAA0265)

产品说明书

Anti-Human TIF1/TRIM24 IP Recombinant Antibody (SAA0265).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TIF1/TRIM24 IP Recombinant Antibody (SAA0265) (HT332013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TIF1/TRIM24 IP Recombinant Antibody (SAA0265) (HT332013)

概述

图片

参考文献

产品说明书

相关产品推荐

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