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Anti-Human SLC35B1 Recombinant Antibody (SAA2353) (HC089013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

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概述
货号HC089013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG
克隆号SAA2353
靶标Solute carrier family 35 member B1, ATP/ADP exchanger ER, AXER, Endoplasmic reticulum ATP/ADP translocase, UDP-galactose transporter-related protein 1, UGTrel1, SLC35B1, UGTREL1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P78383
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Solute carrier family 35 member B1 (SLC35B1) is a ~35 kDa protein. ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane. Imports ATP from the cytosol to the ER lumen and exports ADP in the opposite direction. Regulates ER energy metabolism and protein biogenesis. Appears to be part of a calcium-dependent ER to cytosol low energy response axis, where calcium efflux from ER to the cytosol triggers ATP import into the ER lumen to maintain sufficient ATP supply. Provides ATP to ER chaperone HSPA5 that drives protein folding and trafficking in the ER.

1. Klein, MC. et al. (2018) Nature communications 9, 3489. PMID: 30154480
2. Schwarzbaum, PJ. et al. (2022) The Journal of biological chemistry 298, 101537. PMID: 35041824
3. Gulati, A. et al. (2025) Nature 643, 855-864. PMID: 40399679
NoteFor research use only
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human SLC35B1 Antibody (SAA2353)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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