| 货号 | HW310063 |
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| 品牌 | abinScience |
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| 种属反应性 | Human |
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| 应用 | ELISA, FACS, Functional assay |
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| 宿主 | Human |
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| 克隆类型 | Monoclonal |
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| 同种型 | IgG1, kappa |
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| 克隆号 | HS20 |
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| 靶标 | pan-Glypican, heparan sulfate, Glypican-1, Secreted glypican-1, GPC1, Glypican-2, Secreted glypican-2, GPC2, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Glypican-3 alpha subunit, Glypican-3 beta subunit, GPC3, OCI5, Glypican-4, K-glypican, Secreted glypican-4, GPC4, Glypican-5, Secreted glypican-5, GPC5, Glypican-6, Secreted glypican-6, GPC6 |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 纯度 | >95% as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| Accession号 | P35052, Q8N158, I6QTG3, O75487, P78333, Q9Y625 |
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| 状态 | Liquid |
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| 保存溶液 |
0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
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| 产品使用信息 |
| 应用方法 |
稀释比例 |
| ELISA |
1:2000-1:20000 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
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| 背景 | Glypican-1 (pan-Glypican) is a ~61 kDa protein. Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. |
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| Note | For research use only |
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| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
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