Anti-PACAP38 Recombinant Antibody (Lilly patent anti-PACAP) (HB716013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HB716013

abinScience

种属反应性

Human

ELISA, FACS, Functional assay

Human

Monoclonal

IgG4, kappa

Lilly patent anti-PACAP

Pituitary adenylate cyclase-activating polypeptide, PACAP, PACAP-related peptide, PRP-48, Pituitary adenylate cyclase-activating polypeptide 27, PACAP-27, PACAP27, Pituitary adenylate cyclase-activating polypeptide 38, PACAP-38, PACAP38, ADCYAP1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P18509

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Pituitary adenylate cyclase-activating polypeptide (PACAP38) is a ~18 kDa protein. PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor (ADCYAP1R1). Exerts neuroprotective and general cytoprotective effects due to anti-apoptotic, anti-inflammatory, and antioxidant actions. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

1. Inooka, H. et al. (2001) Nature structural biology 8, 161-5. PMID: 11175907

2. Emery, AC. et al. (2013) Science signaling 6, ra51. PMID: 23800469

3. Wang, J. et al. (2020) Cell research 30, 436-445. PMID: 32047270

4. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145

For research use only

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

SDS-PAGE

SDS-PAGE for Anti-PACAP38 Antibody (Lilly patent anti-PACAP)

产品说明书

Anti-PACAP38 Recombinant Antibody (Lilly patent anti-PACAP).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PACAP38 Recombinant Antibody (Lilly patent anti-PACAP) (HB716013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PACAP38 Recombinant Antibody (Lilly patent anti-PACAP) (HB716013)

概述

图片

参考文献

产品说明书

相关产品推荐

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