Anti-Human S100A4 Recombinant Antibody (5C3) (HB727013)

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50ug
100ug
1mg

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货号	HB727013
品牌	abinScience
种属反应性	Monkey, Macaca mulatta (Rhesus macaque)
应用	FuncS, IHC, Neut, Inhib
宿主	Mouse
克隆类型	Monoclonal
同种型	IgG1, kappa
克隆号	5C3
靶标	Protein S100-A4, Calvasculin, Metastasin, Placental calcium-binding protein, Protein Mts1, S100 calcium-binding protein A4, S100A4, CAPL, MTS1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P26447, P07091
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Protein S100-A4 (S100A4) is a ~11 kDa protein. Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. 1. Li, ZH. et al. (2006) Cancer research 66, 5173-80. PMID: 16707441 2. Orre, LM. et al. (2013) Oncogene 32, 5531-40. PMID: 23752197 3. Sharapova, TN. et al. (2018) Acta naturae 10, 115-120. PMID: 30713770 4. Dukhanina, EA. et al. (2015) Cell cycle (Georgetown, Tex.) 14, 3635-43. PMID: 26654597
Note	For research use only

SDS-PAGE

SDS-PAGE for Anti-Human S100A4 Antibody (5C3)

产品说明书

Anti-Human S100A4 Recombinant Antibody (5C3).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-Human S100A4 Recombinant Antibody (5C3) (HB727013)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human S100A4 Recombinant Antibody (5C3) (HB727013)

概述

图片

参考文献

产品说明书

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