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Anti-Human GREM1 Recombinant Antibody (SAA2524) (MT246013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号MT246013
品牌abinScience
种属反应性Mouse
应用ELISA, FACS, Functional assay
宿主Mouse
克隆类型Monoclonal
同种型IgG1
克隆号SAA2524
靶标Cktsf1b1, Cysteine knot superfamily 1, BMP antagonist 1, Down-regulated in Mos-transformed cells protein, Drm, Grem1, Gremlin-1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O70326
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Gremlin-1 (GREM1) is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis.

1. Khokha, MK. et al. (2003) Nature genetics 34, 303-7. PMID: 12808456
2. Michos, O. et al. (2004) Development (Cambridge, England) 131, 3401-10. PMID: 15201225
3. Pangas, SA. et al. (2004) The Journal of biological chemistry 279, 32281-6. PMID: 15133038
NoteFor research use only
Isotype ControlMouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human GREM1 Antibody (SAA2524)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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