Anti-Human Human CYP19A1 Recombinant Antibody (SAA2693) (HY384013)

价格:

规格：

50ug
100ug
1mg

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HY384013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA2693

ARO1, Aromatase, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, EC:1.14.14.14, Estrogen synthase

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P11511

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Aromatase (CYP19A1) is a ~57 kDa protein. A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively. Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19-aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid. Alternatively, the third oxidative reaction yields a 19-norsteroid and formic acid. Converts dihydrotestosterone to delta1,10-dehydro 19-nordihydrotestosterone and may play a role in homeostasis of this potent androgen. Also displays 2-hydroxylase activity toward estrone.

1. Baravalle, R. et al. (2017) The Journal of steroid biochemistry and molecular biology 167, 23-32. PMID: 27702664

2. Corbin, CJ. et al. (1988) Proceedings of the National Academy of Sciences of the United States of America 85, 8948-52. PMID: 2848247

3. Sohl, CD. et al. (2010) The Journal of biological chemistry 285, 17734-43. PMID: 20385561

4. Cheng, Q. et al. (2012) The Journal of biological chemistry 287, 29554-67. PMID: 22773874

For research use only

产品说明书

Anti-Human Human CYP19A1 Recombinant Antibody (SAA2693).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Human CYP19A1 Recombinant Antibody (SAA2693) (HY384013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Human CYP19A1 Recombinant Antibody (SAA2693) (HY384013)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价