Anti-MIS/AMH Recombinant Antibody (SAA2666) (HY076023)

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100ug
1mg

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货号	HY076023
品牌	abinScience
种属反应性	Human, Mouse
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Monoclonal
同种型	IgG
克隆号	SAA2666
靶标	AMH, Anti-Muellerian hormone, MIF, MIS, Muellerian-inhibiting factor, Muellerian-inhibiting substance
内毒素水平	<10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P03971
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Anti-Muellerian hormone (AMH) is a ~59 kDa protein. The anti-Muellerian hormone (AMH) plays an important role in several reproductive functions. Anti-Muellerian hormone binds and activates AMHR2, its specific type-II receptor, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A) to regulate target gene expression through downstream SMAD protein signal transduction. Produced and secreted by Sertoli cells of the male fetus, anti-Muellerian hormone induces Muellerian duct regression during male fetal sexual differentiation. In female, it is produced by granulosa cells of the preantral and small antral follicles and acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. Also plays a role in Leydig cell differentiation and function. 1. Weenen, C. et al. (2004) Molecular human reproduction 10, 77-83. PMID: 14742691 2. Hart, KN. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34155118 3. Cate, RL. et al. (1986) Cell 45, 685-98. PMID: 3754790 4. Wilson, CA. et al. (1993) Molecular endocrinology (Baltimore, Md.) 7, 247-57. PMID: 8469238 5. di Clemente, N. et al. (2010) Molecular endocrinology (Baltimore, Md.) 24, 2193-206. PMID: 20861221
Note	For research use only

产品说明书

Anti-MIS/AMH Recombinant Antibody (SAA2666).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

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Anti-MIS/AMH Recombinant Antibody (SAA2666) (HY076023)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MIS/AMH Recombinant Antibody (SAA2666) (HY076023)

概述

图片

参考文献

产品说明书

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