Anti-HEV ORF3 Recombinant Antibody (SAA2695) (VK620073)

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1mg

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货号	VK620073
品牌	abinScience
种属反应性	Hepatitis E virus (HEV)
应用	ELISA, IF, WB
宿主	Human
克隆类型	Monoclonal
同种型	IgG1
克隆号	SAA2695
靶标	Protein ORF3
内毒素水平	<10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	E9N3C1
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Protein ORF3 is a ~11 kDa protein. Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Also acts as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by down-regulating host TLR3 and TLR7 as well as their downstream signaling pathways. Down-regulates the phosphorylation of host IRF3 via the interaction with host SIRP-alpha, thereby inhibiting IFN-I expression.
Note	For research use only

产品说明书

Anti-HEV ORF3 Recombinant Antibody (SAA2695).pdf

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Anti-HEV ORF3 Recombinant Antibody (SAA2695) (VK620073)

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产品说明书

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实验相关试剂

Anti-HEV ORF3 Recombinant Antibody (SAA2695) (VK620073)

概述

图片

参考文献

产品说明书

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