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Anti-Human CCL17/TARC Recombinant Antibody (Iv0083) (HV615013)

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  • 1mg
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概述
货号HV615013
品牌abinScience
种属反应性Human
应用ELISA, In vivo Neutralization
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号Iv0083
靶标C-C motif chemokine 17, CC chemokine TARC, CCL17, SCYA17, Small-inducible cytokine A17, TARC, Thymus and activation-regulated chemokine
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q92583
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Imai, T. et al. (1996) The Journal of biological chemistry 271, 21514-21. PMID: 8702936
2. Imai, T. et al. (1997) The Journal of biological chemistry 272, 15036-42. PMID: 9169480
3. Garlisi, CG. et al. (1999) European journal of immunology 29, 3210-5. PMID: 10540332
4. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438
NoteFor research use only
Isotype ControlMouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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