Anti-Mouse CD28 Recombinant Antibody (PV-1) (MY422023)

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规格：

50ug
100ug
1mg

数量：

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概述
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参考文献
产品说明书

MY422023

abinScience

种属反应性

Mouse

ELISA, FACS, Functional assay, Research in vivo, in vitro T cell stimulation/activation

Armenian hamster

Monoclonal

CD28, Cd28, T-cell-specific surface glycoprotein CD28

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P31041

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

T-cell-specific surface glycoprotein CD28 is a ~25 kDa protein. Receptor that plays a role in T-cell activation, proliferation, survival and the maintenance of immune homeostasis. Functions not only as an amplifier of TCR signals but delivers unique signals that control intracellular biochemical events that alter the gene expression program of T-cells. Stimulation upon engagement of its cognate ligands CD80 or CD86 increases proliferation and expression of various cytokines in particular IL2 production in both CD4(+) and CD8(+) T-cell subsets. Mechanistically, ligation induces recruitment of protein kinase C-theta/PRKCQ and GRB2 leading to NF-kappa-B activation via both PI3K/Akt-dependent and -independent pathways. In conjunction with TCR/CD3 ligation and CD40L costimulation, enhances the production of IL4 and IL10 in T-cells.

1. Shahinian, A. et al. (1993) Science (New York, N.Y.) 261, 609-12. PMID: 7688139

For research use only

产品说明书

Anti-Mouse CD28 Recombinant Antibody (PV-1).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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实验相关试剂

Anti-Mouse CD28 Recombinant Antibody (PV-1) (MY422023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD28 Recombinant Antibody (PV-1) (MY422023)

概述

图片

参考文献

产品说明书

相关产品推荐

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