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Anti-DCD Polyclonal Antibody (HX130014)

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概述
货号HX130014
品牌abinScience
描述
Anti-DCD Polyclonal Antibody (HX130014) is a rabbit polyclonal antibody detecting DCD in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human DCD (Cys18-Leu110).
靶标DCD, AIDD, DSEP, Dermcidin, Preproteolysin
纯化方式Purified by antigen affinity column.
Accession号P81605
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Dermcidin (DCD) is a ~11 kDa protein. Found in sweat, has an antimicrobial activity during early bacterial colonization. The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes. Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat.

1. Schittek, B. et al. (2001) Nature immunology 2, 1133-7. PMID: 11694882
2. Song, C. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4586-91. PMID: 23426625
3. Lee Motoyama, JP. et al. (2007) Biochemical and biophysical research communications 357, 828-33. PMID: 17448443
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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