

| 货号 | HX130014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-DCD Polyclonal Antibody (HX130014) is a rabbit polyclonal antibody detecting DCD in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human DCD (Cys18-Leu110). | ||||||||
| 靶标 | DCD, AIDD, DSEP, Dermcidin, Preproteolysin | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P81605 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Dermcidin (DCD) is a ~11 kDa protein. Found in sweat, has an antimicrobial activity during early bacterial colonization. The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes. Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. 1. Schittek, B. et al. (2001) Nature immunology 2, 1133-7. PMID: 11694882 2. Song, C. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4586-91. PMID: 23426625 3. Lee Motoyama, JP. et al. (2007) Biochemical and biophysical research communications 357, 828-33. PMID: 17448443 | ||||||||
| Note | For research use only. |

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