

| 货号 | HX843014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-IRF9 Polyclonal Antibody (HX843014) is a rabbit polyclonal antibody detecting IRF9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human IRF9 (Met1-Val393). | ||||||||
| 靶标 | Interferon regulatory factor 9, ISGF3G, IRF-9, ISGF-3 gamma, ISGF3 p48 subunit, Transcriptional regulator ISGF3 subunit gamma, IRF9, Interferon-stimulated gene factor 3 gamma, IFN-alpha-responsive transcription factor subunit | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q00978 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Interferon regulatory factor 9 (IRF9) is a ~43 kDa protein. Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. | ||||||||
| Note | For research use only. |

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