Anti-FADD Polyclonal Antibody (HC591014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HC591014

品牌

abinScience

描述

Anti-FADD Polyclonal Antibody (HC591014) is a rabbit polyclonal antibody detecting FADD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human FADD (Ser12-Glu206).

靶标

Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, MORT1, FAS-associating death domain-containing protein, FAS-associated death domain protein, FADD, Protein FADD

纯化方式

Purified by antigen affinity column.

Accession号

Q13158

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

FAS-associated death domain protein (FADD) is a ~23 kDa protein. Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

1. Carrington, PE. et al. (2006) Molecular cell 22, 599-610. PMID: 16762833

2. Scott, FL. et al. (2009) Nature 457, 1019-22. PMID: 19118384

3. Wang, L. et al. (2010) Nature structural & molecular biology 17, 1324-9. PMID: 20935634

4. Li, S. et al. (2013) Nature 501, 242-6. PMID: 23955153

5. Pearson, JS. et al. (2013) Nature 501, 247-51. PMID: 24025841

6. Chinnaiyan, AM. et al. (1995) Cell 81, 505-12. PMID: 7538907

7. Medema, JP. et al. (1997) The EMBO journal 16, 2794-804. PMID: 9184224

Note

For research use only.

图片

参考文献

产品说明书

Anti-FADD Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-FADD Polyclonal Antibody (HC591014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-FADD Polyclonal Antibody (HC591014)

概述

图片

参考文献

产品说明书

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