

| 货号 | HC307014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-PTCH1 Polyclonal Antibody (HC307014) is a rabbit polyclonal antibody detecting PTCH1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Chicken.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human PTCH1 (Glu122-Leu249). | ||||||||
| 靶标 | Protein patched homolog 1, PTC1, PTCH, PTCH1, PTC | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q13635 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein patched homolog 1 (PTCH1) is a ~160 kDa protein. Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis. | ||||||||
| Note | For research use only. |

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