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Anti-ACOX1 Polyclonal Antibody (HS771014)

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概述
货号HS771014
品牌abinScience
描述
Anti-ACOX1 Polyclonal Antibody (HS771014) is a rabbit polyclonal antibody detecting ACOX1 in ELISA, IHC, WB. Suitable for Bovine, Cavia porcellus, Human, Pongo abelii, and Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human ACOX1 (Tyr275-Leu660).
靶标ACOX1, Palmitoyl-CoA oxidase, SCOX, AOX, ACOX, Peroxisomal acyl-coenzyme A oxidase 1, Straight-chain acyl-CoA oxidase
纯化方式Purified by antigen affinity column.
Accession号Q15067
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) is a ~74 kDa protein. Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)).

1. Ferdinandusse, S. et al. (2004) Journal of lipid research 45, 1104-11. PMID: 15060085
2. Ferdinandusse, S. et al. (2007) Human mutation 28, 904-12. PMID: 17458872
3. Oaxaca-Castillo, D. et al. (2007) Biochemical and biophysical research communications 360, 314-9. PMID: 17603022
4. Chung, HL. et al. (2020) Neuron 106, 589-606.e6. PMID: 32169171
5. Morita, A. et al. (2021) Brain & development 43, 475-481. PMID: 33234382
6. Chu, R. et al. (1995) The Journal of biological chemistry 270, 4908-15. PMID: 7876265
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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