

| 货号 | HV002014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-RRM2B Polyclonal Antibody (HV002014) is a rabbit polyclonal antibody detecting RRM2B in ELISA, IHC, WB. Suitable for Human, Mouse, Macaca fascicularis, and Pongo abelii.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human RRM2B (Met1-Phe351). | ||||||||
| 靶标 | p53R2, p53-inducible ribonucleotide reductase small subunit 2-like protein, P53R2, RRM2B, TP53-inducible ribonucleotide reductase M2 B, Ribonucleoside-diphosphate reductase subunit M2 B | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q7LG56 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) is a ~40 kDa protein. Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage. | ||||||||
| Note | For research use only. |

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