

| 货号 | HV121014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-IL31RA Polyclonal Antibody (HV121014) is a rabbit polyclonal antibody detecting IL31RA in ELISA, IHC, WB. Suitable for Human.
Highlights
| ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human IL31RA (Val130-Asp622). | ||||||||
| 靶标 | IL-31RA, Interleukin-31 receptor subunit alpha, IL31RA, hGLM-R, ZcytoR17, IL-31R-alpha, GPL, CRL3, Cytokine receptor-like 3, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like receptor, GLM-R, Gp130-like monocyte receptor | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8NI17 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. 1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449 2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285 3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700 4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637 5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理