

| 货号 | HV042014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-HDAC10 Polyclonal Antibody (HV042014) is a rabbit polyclonal antibody detecting HDAC10 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human HDAC10 (Met1-Gln358). | ||||||||
| 靶标 | HDAC10, Polyamine deacetylase HDAC10, HD10, Histone deacetylase 10 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q969S8 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Polyamine deacetylase HDAC10 is a ~71 kDa protein. Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. 1. Hai, Y. et al. (2017) Nature communications 8, 15368. PMID: 28516954 2. Kao, HY. et al. (2002) The Journal of biological chemistry 277, 187-93. PMID: 11677242 3. Guardiola, AR. et al. (2002) The Journal of biological chemistry 277, 3350-6. PMID: 11726666 4. Fischer, DD. et al. (2002) The Journal of biological chemistry 277, 6656-66. PMID: 11739383 5. Tong, JJ. et al. (2002) Nucleic acids research 30, 1114-23. PMID: 11861901 6. Radhakrishnan, R. et al. (2015) The Journal of biological chemistry 290, 22795-804. PMID: 26221039 7. Oehme, I. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, E2592-601. PMID: 23801752 8. Ridinger, J. et al. (2018) Scientific reports 8, 10039. PMID: 29968769 | ||||||||
| Note | For research use only. |

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