

| 货号 | HV660014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-UACA Polyclonal Antibody (HV660014) is a rabbit polyclonal antibody detecting UACA in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, and Bovine.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human UACA (Ala29-Glu209). | ||||||||
| 靶标 | UACA, KIAA1561, Uveal autoantigen with coiled-coil domains and ankyrin repeats | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9BZF9 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) is a ~162 kDa protein. Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. | ||||||||
| Note | For research use only. |

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