

| 货号 | HV242014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-SYTL2 Polyclonal Antibody (HV242014) is a rabbit polyclonal antibody detecting SYTL2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human SYTL2 (Met559-Leu880). | ||||||||
| 靶标 | Breast cancer-associated antigen SGA-72M, SYTL2, Synaptotagmin-like protein 2, SGA72M, SLP2, Exophilin-4, SLP2A, KIAA1597 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9HCH5 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Synaptotagmin-like protein 2 (SYTL2) is a ~104 kDa protein. Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive. | ||||||||
| Note | For research use only. |

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