Anti-NOX4 Polyclonal Antibody (HV319014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HV319014

品牌

abinScience

描述

Anti-NOX4 Polyclonal Antibody (HV319014) is a rabbit polyclonal antibody detecting NOX4 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human NOX4 (Gly210-Glu424).

靶标

RENOX, NOX4, Renal NAD(P)H-oxidase, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1

纯化方式

Purified by antigen affinity column.

Accession号

Q9NPH5

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

NADPH oxidase 4 (NOX4) is a ~66 kDa protein. NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2. Can also catalyze to a smaller extent, the reduction of oxygen to superoxide. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

1. Mahadev, K. et al. (2004) Molecular and cellular biology 24, 1844-54. PMID: 14966267

2. Park, HS. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3589-93. PMID: 15356101

3. Martyn, KD. et al. (2006) Cellular signalling 18, 69-82. PMID: 15927447

4. Takac, I. et al. (2011) The Journal of biological chemistry 286, 13304-13. PMID: 21343298

5. Nisimoto, Y. et al. (2014) Biochemistry 53, 5111-20. PMID: 25062272

6. Geiszt, M. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8010-4. PMID: 10869423

7. Shiose, A. et al. (2001) The Journal of biological chemistry 276, 1417-23. PMID: 11032835

8. Vaquero, EC. et al. (2004) The Journal of biological chemistry 279, 34643-54. PMID: 15155719

9. Pedruzzi, E. et al. (2004) Molecular and cellular biology 24, 10703-17. PMID: 15572675

Note

For research use only.

图片

参考文献

产品说明书

Anti-NOX4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-NOX4 Polyclonal Antibody (HV319014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-NOX4 Polyclonal Antibody (HV319014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价