Anti-CD113/NECTIN3 Polyclonal Antibody (HV970014)

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100ug

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概述
图片
参考文献
产品说明书

概述

货号

HV970014

品牌

abinScience

描述

Anti-CD113/NECTIN3 Polyclonal Antibody (HV970014) is a rabbit polyclonal antibody detecting NECTIN3 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD113/NECTIN3 (Thr171-Ser356).

靶标

CDw113, PRR3, PVRL3, Poliovirus receptor-related protein 3, NECTIN3, Nectin cell adhesion molecule 3, CD113, Nectin-3

纯化方式

Purified by antigen affinity column.

Accession号

Q9NQS3

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Nectin-3 (CD113/NECTIN3) is a ~61 kDa protein. Cell adhesion molecule that promotes cell-cell adhesion through heterophilic trans-interactions with nectins-like or other nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Involved in axon guidance by promoting contacts between the commissural axons and the floor plate cells. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses.

1. Fujito, T. et al. (2005) The Journal of cell biology 171, 165-73. PMID: 16216929

Note

For research use only.

图片

参考文献

产品说明书

Anti-CD113/NECTIN3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD113/NECTIN3 Polyclonal Antibody (HV970014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD113/NECTIN3 Polyclonal Antibody (HV970014)

概述

图片

参考文献

产品说明书

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