Anti-PLA2G2D Polyclonal Antibody (HV752014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HV752014

品牌

abinScience

描述

Anti-PLA2G2D Polyclonal Antibody (HV752014) is a rabbit polyclonal antibody detecting PLA2G2D in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human PLA2G2D (Gly21-Cys145).

靶标

PLA2IID, SPLASH, Group IID secretory phospholipase A2, sPLA2-IID, Secretory-type PLA, stroma-associated homolog, GIID sPLA2, Phosphatidylcholine 2-acylhydrolase 2D, PLA2G2D

纯化方式

Purified by antigen affinity column.

Accession号

Q9UNK4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Group IID secretory phospholipase A2 (PLA2G2D) is a ~16 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets extracellular lipids, exerting anti-inflammatory and immunosuppressive functions. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines. In draining lymph nodes, selectively hydrolyzes diacyl and alkenyl forms of phosphatidylethanolamines, releasing omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoate and docosahexaenoate that are precursors of the anti-inflammatory lipid mediators, resolvins. During the resolution phase of acute inflammation drives docosahexaenoate-derived resolvin D1 synthesis, which suppresses dendritic cell activation and T-helper 1 immune response. May act in an autocrine and paracrine manner.

1. Ishizaki, J. et al. (1999) The Journal of biological chemistry 274, 24973-9. PMID: 10455175

2. Suzuki, N. et al. (2000) The Journal of biological chemistry 275, 5785-93. PMID: 10681567

Note

For research use only.

图片

参考文献

产品说明书

Anti-PLA2G2D Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PLA2G2D Polyclonal Antibody (HV752014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PLA2G2D Polyclonal Antibody (HV752014)

概述

图片

参考文献

产品说明书

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