

| 货号 | HV794014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-HPSE Polyclonal Antibody (HV794014) is a rabbit polyclonal antibody detecting HPSE in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human HPSE (Gln34-Arg115). | ||||||||
| 靶标 | Hpa1, HPA1, Heparanase-1, HSE1, HEP, Heparanase, Endo-glucoronidase, HPSE1, HPA, HPR1, HPSE | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9Y251 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Heparanase (HPSE) is a ~61 kDa protein. Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety. It is essentially inactive at neutral pH but becomes active under acidic conditions such as during tumor invasion and in inflammatory processes. | ||||||||
| Note | For research use only. |

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