Anti-MAP2K7 Polyclonal Antibody (HT186014)

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概述
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参考文献
产品说明书

概述

货号

HT186014

品牌

abinScience

描述

Anti-MAP2K7 Polyclonal Antibody (HT186014) is a rabbit polyclonal antibody detecting MAP2K7 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human MAP2K7 (Thr103-Arg419).

靶标

SAPKK4, JNK-activating kinase 2, MAPK/ERK kinase 7, MAPKK 7, c-Jun N-terminal kinase kinase 2, JNKK2, SAPK kinase 4, MEK 7, MAP kinase kinase 7, SKK4, PRKMK7, Dual specificity mitogen-activated protein kinase kinase 7, Stress-activated protein kinase kinase 4, JNK kinase 2, MKK7, MAP2K7, MEK7, JNKK 2, SAPKK-4

纯化方式

Purified by antigen affinity column.

Accession号

O14733

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7) is a ~47 kDa protein. Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue.

1. Huang, YA. et al. (2017) Cell 168, 427-441.e21. PMID: 28111074

Note

For research use only.

图片

参考文献

产品说明书

Anti-MAP2K7 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MAP2K7 Polyclonal Antibody (HT186014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MAP2K7 Polyclonal Antibody (HT186014)

概述

图片

参考文献

产品说明书

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