首页 > 产品中心 > 抗体 > 一抗

Anti-Human CD59 Polyclonal Antibody (HB615014)

价格:
规格:
  • 50ug
  • 100ug
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HB615014
品牌abinScience
描述
Anti-CD59 Polyclonal Antibody (HB615014) is a rabbit polyclonal antibody detecting CD59 in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CD59 (Leu26-Asn102).
靶标MSK21, MAC-inhibitory protein, MEM43 antigen, MAC-IP, MIN2, MIRL, HRF20, Protectin, 1F5 antigen, MIC11, MIN3, Membrane inhibitor of reactive lysis, MACIF, 20 kDa homologous restriction factor, CD59, MIN1, CD59 glycoprotein, HRF-20, Membrane attack complex inhibition factor
纯化方式Purified by antigen affinity column.
Accession号P13987
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

CD59 glycoprotein is a ~14 kDa protein. Potent inhibitor of the complement membrane attack complex (MAC) action, which protects human cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore.

1. Farkas, I. et al. (2002) The Journal of physiology 539, 537-45. PMID: 11882685
2. Meri, S. et al. (1990) Immunology 71, 1-9. PMID: 1698710
3. Okada, H. et al. (1989) Biochemical and biophysical research communications 162, 1553-9. PMID: 2475111
4. Davies, A. et al. (1989) The Journal of experimental medicine 170, 637-54. PMID: 2475570
5. Sugita, Y. et al. (1989) Journal of biochemistry 106, 555-7. PMID: 2606909
6. Bodian, DL. et al. (1997) The Journal of experimental medicine 185, 507-16. PMID: 9053451
7. Couves, EC. et al. (2023) Nature communications 14, 890. PMID: 36797260
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐