Anti-S100A12 Polyclonal Antibody (HX203014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HX203014

品牌

abinScience

描述

Anti-S100A12 Polyclonal Antibody (HX203014) is a rabbit polyclonal antibody detecting S100A12 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human S100A12 (Met1-Glu92).

靶标

Migration inhibitory factor-related protein 6, MRP-6, Extracellular newly identified RAGE-binding protein, p6, Calcium-binding protein in amniotic fluid 1, Calgranulin-C, Protein S100-A12, CGRP, S100 calcium-binding protein A12, Neutrophil S100 protein, CAAF1, EN-RAGE, S100A12, CAGC

纯化方式

Purified by antigen affinity column.

Accession号

P80511

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Protein S100-A12 (S100A12) is a ~10 kDa protein. S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its pro-inflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of pro-inflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. Acts as a monocyte and mast cell chemoattractant.

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-S100A12 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Human blood lysate
Lane 2: Human blood lysate
Lane 3: Mouse lung lysate
Lane 4: Mouse liver lysate
Lane 5: Mouse spleen lysate
Lane 6: Rat lung lysate
Lane 7: Rat liver lysate
Lane 8: Rat spleen lysate

参考文献

产品说明书

Anti-S100A12 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-S100A12 Polyclonal Antibody (HX203014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-S100A12 Polyclonal Antibody (HX203014)

概述

图片

参考文献

产品说明书

相关产品推荐

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