

| 货号 | HV550014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-WDFY1 Polyclonal Antibody (HV550014) is a rabbit polyclonal antibody detecting WDFY1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human WDFY1 (Met1-His410). | ||||||||
| 靶标 | FENS-1, Zinc finger FYVE domain-containing protein 17, WD40- and FYVE domain-containing protein 1, FYVE domain-containing protein localized to endosomes 1, KIAA1435, ZFYVE17, WDFY1, FENS1, WD repeat and FYVE domain-containing protein 1, Phosphoinositide-binding protein 1, WDF1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8IWB7 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | WD repeat and FYVE domain-containing protein 1 (WDFY1) is a ~46 kDa protein. Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines. 1. Hu, YH. et al. (2015) EMBO reports 16, 447-55. PMID: 25736436 | ||||||||
| Note | For research use only. |

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