

| 货号 | AY583024 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Tocilizumab Polyclonal Antibody (AY583024) is a rabbit polyclonal antibody detecting Tocilizumab in ELISA.
Highlights
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| 种属反应性 | General | ||||||||
| 应用 | ELISA | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | Tocilizumab | ||||||||
| 靶标 | Rabbit polyclonal to Actemra. | ||||||||
| 特异性 | The product is specific for Tocilizumab. This antibody serves as an excellent positive control for Tocilizumab immunogenicity (ADA) assays. | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯度 | >90% as determined by SDS-PAGE. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | CAS: 375823-41-9 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann–La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects. • Evaluation of a biosensor immunoassay for simultaneous characterization of isotype and binding region of human anti-tocilizumab antibodies with control by surrogate standards., PMID:19379704 | ||||||||
| Note | For research use only. |

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