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Anti-Human SRCAP Polyclonal Antibody (HP108014)

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概述
货号HP108014
品牌abinScience
描述
Anti-Human SRCAP Polyclonal Antibody (HP108014) is a rabbit polyclonal antibody detecting SRCAP in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human SRCAP (Lys2044-Thr2197).
靶标Helicase SRCAP, 3.6.4.-, Domino homolog 2, Snf2-related CBP activator, SRCAP, KIAA0309
纯化方式Purified by antigen affinity column.
Accession号Q6ZRS2
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Chromatin remodeling protein SRCAP is a ~343 kDa protein. Acts both as a chromatin remodeler and transcription coregulator. Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes expression through chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription.

1. Ruhl, DD. et al. (2006) Biochemistry 45, 5671-7. PMID: 16634648
2. Wong, MM. et al. (2007) The Journal of biological chemistry 282, 26132-9. PMID: 17617668
3. Johnston, H. et al. (1999) The Journal of biological chemistry 274, 16370-6. PMID: 10347196
4. Monroy, MA. et al. (2001) The Journal of biological chemistry 276, 40721-6. PMID: 11522779
5. Monroy, MA. et al. (2003) Molecular endocrinology (Baltimore, Md.) 17, 2519-28. PMID: 14500758
6. Eissenberg, JC. et al. (2005) Molecular and cellular biology 25, 6559-69. PMID: 16024792
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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