Anti-Human TRPM4/LTRPC4 Polyclonal Antibody (HP790014)

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100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HP790014

品牌

abinScience

描述

Anti-Human TRPM4/LTRPC4 Polyclonal Antibody (HP790014) is a rabbit polyclonal antibody detecting LTRPC4 in ELISA, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

种属反应性

Human

应用

ELISA, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

Synthetic peptides.

靶标

LTRPC4, Transient receptor potential cation channel subfamily M member 4, TRPM4, Melastatin-4, LTrpC-4, hTRPM4, Calcium-activated non-selective cation channel 1, LTrpC4, Long transient receptor potential channel 4

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q8TD43

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Transient receptor potential cation channel subfamily M member 4 (TRPM4/LTRPC4) is a ~134 kDa protein. Calcium-activated selective cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production.

1. Launay, P. et al. (2002) Cell 109, 397-407. PMID: 12015988

2. Hofmann, T. et al. (2003) Current biology : CB 13, 1153-8. PMID: 12842017

3. Winkler, PA. et al. (2017) Nature 552, 200-204. PMID: 29211723

4. Wang, H. et al. (2019) The Journal of investigative dermatology 139, 1089-1097. PMID: 30528822

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human TRPM4/LTRPC4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRPM4/LTRPC4 Polyclonal Antibody (HP790014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRPM4/LTRPC4 Polyclonal Antibody (HP790014)

概述

图片

参考文献

产品说明书

相关产品推荐

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