Anti-CD49f/ITGA6 Polyclonal Antibody (HB157014)

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50ug
100ug

数量：

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概述
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产品说明书

概述

货号

HB157014

品牌

abinScience

描述

Anti-CD49f/ITGA6 Polyclonal Antibody (HB157014) is a rabbit polyclonal antibody detecting ITGA6 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD49f/ITGA6 (Ala23-Gln462).

靶标

CD49 antigen-like family member F, Integrin alpha-6, ITGA6, VLA-6, CD49f, Alpha6p

纯化方式

Purified by antigen affinity column.

Accession号

P23229

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Integrin alpha-6 (CD49f/ITGA6) is a ~126 kDa protein. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling.

1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778

2. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760

3. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464

Note

For research use only.

图片

参考文献

产品说明书

Anti-CD49f/ITGA6 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD49f/ITGA6 Polyclonal Antibody (HB157014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD49f/ITGA6 Polyclonal Antibody (HB157014)

概述

图片

参考文献

产品说明书

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