

| 货号 | HX242014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SRSF2/SC-35 Polyclonal Antibody (HX242014) is a rabbit polyclonal antibody detecting SC-35 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Pan troglodytes.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human SRSF2/SC-35 (Met1-Ser101). | ||||||||
| 靶标 | Splicing factor SC35, Splicing factor, arginine/serine-rich 2, SC-35, Serine/arginine-rich splicing factor 2, SFRS2, SRSF2, Splicing component, 35 kDa, Protein PR264 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q01130 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Serine/arginine-rich splicing factor 2 (SRSF2/SC-35) is a ~25 kDa protein. Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. | ||||||||
| Note | For research use only. |

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