Anti-Rat SCNN1A/SCNN1 Polyclonal Antibody (RW302014)

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100ug

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概述
图片
参考文献
产品说明书

概述

货号

RW302014

品牌

abinScience

描述

Anti-Rat SCNN1A/SCNN1 Polyclonal Antibody (RW302014) is a rabbit polyclonal antibody detecting Scnn1a in ELISA, IHC, WB. Suitable for Human, Mouse, Pan troglodytes, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Rat SCNN1A/SCNN1 (Glu132-Asp391).

靶标

Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA, Scnn1a, Renac

纯化方式

Purified by antigen affinity column.

Accession号

P37089

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Epithelial sodium channel subunit alpha (SCNN1A/SCNN1) is a ~78 kDa protein. This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance.

1. Lingueglia, E. et al. (1994) The Journal of biological chemistry 269, 13736-9. PMID: 8188647

2. Gründer, S. et al. (1997) The EMBO journal 16, 899-907. PMID: 9118951

3. Lingueglia, E. et al. (1993) FEBS letters 318, 95-9. PMID: 8382172

Note

For research use only.

图片

参考文献

产品说明书

Anti-Rat SCNN1A/SCNN1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Rat SCNN1A/SCNN1 Polyclonal Antibody (RW302014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Rat SCNN1A/SCNN1 Polyclonal Antibody (RW302014)

概述

图片

参考文献

产品说明书

相关产品推荐

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