Anti-Human DYNLL1 Polyclonal Antibody (HX228014)

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概述
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参考文献
产品说明书

概述

货号

HX228014

品牌

abinScience

描述

Anti-Human DYNLL1 Polyclonal Antibody (HX228014) is a rabbit polyclonal antibody detecting DYNLL1 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human DYNLL1 (Cys2-Gly89).

靶标

DNCL1, Dynein light chain 1, cytoplasmic, DNCLC1, 8 kDa dynein light chain, DLC1, HDLC1, PIN, Dynein light chain LC8-type 1, DLC8, Protein inhibitor of neuronal nitric oxide synthase, DYNLL1

纯化方式

Purified by antigen affinity column.

Accession号

P63167

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Dynein light chain 1, cytoplasmic (DYNLL1) is a ~10 kDa protein. Component of dynein, a family of motor proteins essential for movement along microtubules. Required for structural and functional integrity of cilia. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.

1. Puthalakath, H. et al. (1999) Molecular cell 3, 287-96. PMID: 10198631

2. Vadlamudi, RK. et al. (2004) Cancer cell 5, 575-85. PMID: 15193260

3. Rayala, SK. et al. (2005) EMBO reports 6, 538-44. PMID: 15891768

4. Rayala, SK. et al. (2006) The Journal of biological chemistry 281, 19092-9. PMID: 16684779

5. He, YJ. et al. (2018) Nature 563, 522-526. PMID: 30464262

6. Swift, ML. et al. (2023) Nature structural & molecular biology 30, 1456-1467. PMID: 37696958

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human DYNLL1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DYNLL1 Polyclonal Antibody (HX228014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DYNLL1 Polyclonal Antibody (HX228014)

概述

图片

参考文献

产品说明书

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