

| 货号 | HP379014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human MIEF1 Polyclonal Antibody (HP379014) is a rabbit polyclonal antibody detecting MIEF1 in ELISA, IHC, WB. Suitable for Human, Mouse, Pongo abelii, and Rat.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human MIEF1 (Ala119-Thr463). | ||||||||
| 靶标 | MID51, SMCR7-like protein, Mitochondrial dynamics protein MID51, MIEF1, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like, Mitochondrial dynamics protein of 51 kDa, SMCR7L | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9NQG6 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Mitochondrial dynamics protein MIEF1 is a ~51 kDa protein. Mitochondrial outer membrane protein which regulates mitochondrial fission/fusion dynamics. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. 1. Zhao, J. et al. (2011) The EMBO journal 30, 2762-78. PMID: 21701560 2. Palmer, CS. et al. (2013) The Journal of biological chemistry 288, 27584-27593. PMID: 23921378 3. Charif, M. et al. (2021) Molecular neurodegeneration 16, 12. PMID: 33632269 | ||||||||
| Note | For research use only. |

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