Anti-Human ATG7 Polyclonal Antibody (HF840014)

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概述
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参考文献
产品说明书

概述

货号

HF840014

品牌

abinScience

描述

Anti-Human ATG7 Polyclonal Antibody (HF840014) is a rabbit polyclonal antibody detecting ATG7 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human ATG7 (Ser19-Glu321).

靶标

hAGP7, ATG7, Ubiquitin-activating enzyme E1-like protein, APG7L, Ubiquitin-like modifier-activating enzyme ATG7, Autophagy-related protein 7, ATG12-activating enzyme E1 ATG7, APG7-like

纯化方式

Purified by antigen affinity column.

Accession号

O95352

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Ubiquitin-like modifier-activating enzyme ATG7 is a ~77 kDa protein. E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Facilitates LC3-I lipidation with phosphatidylethanolamine to form LC3-II which is found on autophagosomal membranes.

1. Collier, JJ. et al. (2021) The New England journal of medicine 384, 2406-2417. PMID: 34161705

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human ATG7 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATG7 Polyclonal Antibody (HF840014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATG7 Polyclonal Antibody (HF840014)

概述

图片

参考文献

产品说明书

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