Anti-Human KDM3A Polyclonal Antibody (HP526014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HP526014

品牌

abinScience

描述

Anti-Human KDM3A Polyclonal Antibody (HP526014) is a rabbit polyclonal antibody detecting KDM3A in ELISA, IHC, WB. Suitable for Mouse, Chicken, Human, Rat, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human KDM3A (Thr941-Pro1321).

靶标

KIAA0742, KDM3A, JMJD1, Jumonji domain-containing protein 1A, Lysine-specific demethylase 3A, [histone H3]-dimethyl-L-lysine(9) demethylase 3A, JmjC domain-containing histone demethylation protein 2A, TSGA, JHDM2A, JMJD1A

纯化方式

Purified by antigen affinity column.

Accession号

Q9Y4C1

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Lysine-specific demethylase 3A (KDM3A) is a ~147 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin.

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human KDM3A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM3A Polyclonal Antibody (HP526014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM3A Polyclonal Antibody (HP526014)

概述

图片

参考文献

产品说明书

相关产品推荐

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