Anti-Human IFT57 Polyclonal Antibody (HP504014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HP504014

品牌

abinScience

描述

Anti-Human IFT57 Polyclonal Antibody (HP504014) is a rabbit polyclonal antibody detecting IFT57 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human IFT57 (Ala36-Gly160).

靶标

DERP8, Estrogen-related receptor beta-like protein 1, IFT57, Intraflagellar transport protein 57 homolog, ESRRBL1, HIPPI, MHS4R2, HIP1-interacting protein, Dermal papilla-derived protein 8

纯化方式

Purified by antigen affinity column.

Accession号

Q9NWB7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Intraflagellar transport protein 57 homolog (IFT57) is a ~49 kDa protein. Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Together with RAB23 and KIF17, it is required for the localization of specific G protein-coupled receptors, such as dopamime receptor DRD1, to primary cilia. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

1. Leaf, A. et al. (2015) eLife 4. PMID: 26182404

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human IFT57 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human IFT57 Polyclonal Antibody (HP504014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human IFT57 Polyclonal Antibody (HP504014)

概述

图片

参考文献

产品说明书

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