Anti-Human ATG14 Polyclonal Antibody (HP189014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HP189014

品牌

abinScience

描述

Anti-Human ATG14 Polyclonal Antibody (HP189014) is a rabbit polyclonal antibody detecting ATG14 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ATG14 (Glu209-Glu415).

靶标

ATG14L, ATG14, Barkor, Atg14L, Beclin 1-associated autophagy-related key regulator, Autophagy-related protein 14-like protein, KIAA0831

纯化方式

Purified by antigen affinity column.

Accession号

Q6ZNE5

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Beclin 1-associated autophagy-related key regulator (ATG14) is a ~55 kDa protein. Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner.

1. Itakura, E. et al. (2008) Molecular biology of the cell 19, 5360-72. PMID: 18843052

2. Sun, Q. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 19211-6. PMID: 19050071

3. Matsunaga, K. et al. (2009) Nature cell biology 11, 385-96. PMID: 19270696

4. Matsunaga, K. et al. (2010) The Journal of cell biology 190, 511-21. PMID: 20713597

5. Fogel, AI. et al. (2013) Molecular and cellular biology 33, 3675-88. PMID: 23878393

6. Diao, J. et al. (2015) Nature 520, 563-6. PMID: 25686604

7. Shi, X. et al. (2023) Cell reports 42, 113045. PMID: 37632749

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human ATG14 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATG14 Polyclonal Antibody (HP189014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATG14 Polyclonal Antibody (HP189014)

概述

图片

参考文献

产品说明书

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